Solitary cecal ulcers are infrequently encountered cecal lesions. While the majority of cecal lesions are malignant, benign solitary ulcers have been occasionally reported. Clinical presentation of cecal lesions can lead to many differential diagnoses such as inflammatory bowel disease, infectious causes, malignancy, medication, or chemical induced ulcer. To determine the best management for any individual case, diagnosis can be made by colonoscopy and biopsy. A case of solitary ulcer is presented, where the Patient complained of right lower abdominal pain that was treated with conservative management without performing hemi-colectomy. This article also discusses the different aspects of the cecal ulcer with a thorough literature review.