Idiopathic hemophagocytic lymphohistiocytosis in a patient of colitis indeterminate

Oncology, Gastroenterology and Hepatology Reports,2014,3,1,8-10.
Published:January 2014
Type:Case Report
Author(s) affiliations:

Bitoti Chattopadhyay, Atri Chatterjee, Nirod Baran Debnath, Anup Kumar Boler1

Departments of Medicine and 1Pathology, Nilratan Sircar Medical College and Hospital, Kolkata, West Bengal, India


We report a case of a 53‑year‑old male presenting with a history of prolonged fever for one and a half years along with passage of frequent loose stools with occasional hematochezia, significant weight loss and pancytopenia, subsequently diagnosed to suffer from idiopathic hemophagocytic lymphohistiocytosis in the background of non specific colitis. No viral or bacterial pathogen, neoplasm, or autoimmune pathology for such causation could be delineated. To our knowledge this is the first reported case of such an association though very few sporadic case reports of such association with ulcerative colitis and Crohn’s disease have been found in literature.