Epithelial myoepithelial carcinoma of the lower alveolus

Oncology, Gastroenterology and Hepatology Reports,2015,4,1,72-74.
Published:January 2015
Type:Case Report
Author(s) affiliations:

Manigreeva Krishnatreya, Tashnin Rahman, Jagannath D. Sharma1, Amal C. Kataki, Nizara Baishya

Departments of Head and Neck Oncology and 1Pathology, Dr. B Borooah Cancer Institute, Guwahati, Assam, India


Epithelial‑myoepithelial carcinoma (EMC) is a biphasic tumor and classified as a low‑grade tumor of the salivary glands. EMC commonly occurs in the parotids with a reported incidence of around 1% out of all neoplasms of the salivary glands and it is a rare tumor of the minor salivary glands in the oral cavity, especially on the lower alveolus. A 48‑year‑old male patient presented with a rapidly progressive ulcer‑infiltrative growth on the lower alveolus with involvement of the overlying cheek skin in a short span of period. We describe here a case of locally advanced EMC of the lower alveolus, its diagnosis by histopathological examination and immunohistochemical staining, and management by surgery and local external beam radiotherapy (EBRT). In our limited experience in the treatment of EMC on the lower alveolus, wide local excision of the tumor, followed by EBRT had resulted in a good therapeutic outcome at the 3 years posttreatment follow‑up. In conclusion, EMC of the lower alveolar mucosa is extremely rare, and patients should also be advised close follow‑up for the detection of loco‑regional recurrences after treatment.